A subsequent data checked-out this region in more detail using single nucleotide polymorphisms (SNPs) markers in the 3839 teenage twins, the sisters and their parents . The highest relationship having blue/non-blue eye the colour was receive that have three OCA2 SNPs: rs7495174 T/C, rs6497268 G/T and you will rs11855019 T/C in the intron step 1 regarding OCA2. These types of about three SNPs come into one to significant haplotype cut off, with TGT representing 78.4% out of alleles. The brand new TGT/TGT diplotype utilized in 62.2% from products is actually the major genotype seen to modify attention colour, with a volume away from 0.905 from inside the blue otherwise green compared to only 0.095 when you look at the brown eyes along with. A beneficial about three-SNP haplotype for the intron step one out of OCA2 explains extremely eye-along with type. Genome-greater association education (GWAS) to possess attention the color weiterlesen →